We investigated disturbances in dynamic functional connectivity (dFC) in whole-brain networks and altered dynamic functional topology of the brain regarding eigenvector centrality in first-episode drug-free patients with schizophrenia. By using resting-state functional magnetic resonance imaging (rf-MRI) data, schizophrenia was mainly manifested as prolonged dwell time in a state characterized by sparsely connected FCs and increased temporal variability of nodal centrality in the visual network, which may help us better interpret the mechanisms underlying visual and auditory hallucination in schizophrenia.
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