Identifying regional neural pathways with magnetic resonance imaging (MRI) based diffusion characteristics across all possible regions of interest (ROI) is computationally expensive and demands a concerted effort to ensure reliable extraction of tractography statistics from the diffusion tensor imaging data associated with identifiable fiber tracts from a patient’s brain MRI examination. Here we present a software tool called Connectome Reporting User Shell (CRUSH) that processes DTI data using pluggable modules that can be tailored to research specific outcomes. We demonstrate the value of such a tool by conducting a whole-brain tractography-based connectomics analysis on a clinically imaged neurologically healthy population.
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