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Abstract #1535

5-Minute MR Fingerprinting from Acquisition to Reconstruction for Whole-Brain Coverage with Isotropic Submillimeter Resolution

Yilin Liu1, Yong Chen2, and Pew-thian Yap1
1University of North Carolina at Chapel Hill, Chapel Hill, NC, United States, 2Case Western Reserve University, Cleveland, OH, United States

Existing techniques for 3D MR fingerprinting focus on accelerating either acquisition or template matching, with typically limited spatial resolution. We develop a 3D MRF sequence coupled with a novel end-to-end deep learning image reconstruction framework for rapid and simultaneous whole-brain quantification of T1 and T2 relaxation times with isotropic submillimeter spatial resolution. We demonstrate feasibility with both retrospectively and prospectively accelerated 3D MRF data.

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