Abstract #1547

Myelin Water Imaging in the Hybrid State

Andrew Mao^1,2,3, Sebastian Flassbeck^1,2, Cem Gultekin⁴, Xiaoxia Zhang^1,2, and Jakob Asslaender^1,2

¹Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States, ²Center for Advanced Imaging Innovation and Research, New York University School of Medicine, New York, NY, United States, ³Vilcek Institute of Graduate Biomedical Sciences, New York University School of Medicine, New York, NY, United States, ⁴Courant Institute of Mathematical Sciences, New York University, New York, NY, United States

This work extends the recently introduced hybrid-state model to myelin water imaging. We numerically optimize a hybrid-state MR fingerprinting sequence for SNR efficiency and demonstrate in vivo the ability to quantify the myelin water fraction and T2 of axonal/extra-axonal water. Our preliminary results show myelin water fraction maps in agreement with literature and demonstrate the feasibility of simultaneous myelin water fraction, T1 and T2 quantification with high spatial resolution (1.2mm isotropic), full brain coverage with a 14 minute scan.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.