MR Fingerprinting (MRF) allows simultaneous acquisition of multi-parametric maps but the synthetic contrast images suffer from artifacts due to incomplete simulations. This work provides rapid (~4min), natural contrast (non-synthetic), quantitative (T1 and T2 maps), and qualitative images (T1-weighted, T1-FLAIR, T2-weighted, STIR, water,fat) simultaneously. Tailored MRF (TMRF) was demonstrated on four volunteers on 3T GE 750w scanner. It was compared with gold standard (GS) and MRF by computing SNR and mean intensity values of white matter (WM) and grey matter (GM) contrast. The SNR of GS>TMRF>MRF and the contrast for TMRF was greater than MRF and GS.
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