We employed the recent Bingham neurite orientation dispersion and density imaging (NODDI-B) and diffusion kurtosis imaging (DKI) techniques, alongside classical diffusion tensor imaging (DTI) and found that psychotic spectrum disorders (PSD) and PSD sub-types had significantly increased mean and radial diffusion and orientation dispersion (MD, RD, ODI, ODIs) and significantly decreased mean and radial kurtosis (MK, RK), fractional anisotropy (FA) and neurite density index (NDI) in sub-cortical WM ROIs compared to healthy controls (HC). We also found significant relationships across PSD and HC groups between WM dMRI metrics and tests of episodic and working memory and several schizotypal traits.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords