We employed the recent Bingham neurite orientation dispersion and density imaging (NODDI-B) and diffusion kurtosis imaging (DKI) techniques, alongside classical diffusion tensor imaging (DTI) and found that psychotic spectrum disorders (PSD) and PSD sub-types had significantly increased mean and radial diffusion and orientation dispersion (MD, RD, ODI, ODIs) and significantly decreased mean and radial kurtosis (MK, RK), fractional anisotropy (FA) and neurite density index (NDI) in sub-cortical WM ROIs compared to healthy controls (HC). We also found significant relationships across PSD and HC groups between WM dMRI metrics and tests of episodic and working memory and several schizotypal traits.
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