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Abstract #1668

Effect of the outbreak of COVID-19 on college students with subthreshold depression:a resting-state functional MRI study

zhang zhang qi1, pan chen2, ZHEN YE LUO3, Long QIAN4, and YING WANG2
1JINAN UNIVERCITY, guang zhou, China, 2Jinan Univercity, guang zhou, China,, guang zhou, China, 4MR Research, GE Healthcare, Beijing, China., BEI JING, China

Background: The current outbreak of the novel coronavirus disease 2019 (COVID-19), has rapidly spread across China and many other countries.Subthreshold depression (SD) is generally considered to present when individuals show depressive symptoms but diagnostic criteria for a major depressive disorder are not met. Methods: In total,49 SD individuals and 56 health controls(HC) were recruited from Jinan University. All subjects underwent MRI and MATRICS Consensus Cognitive Battery (MCCB) before COVID-19 outbreak. Conclusion: After the COVID-19 epidemic situation, changes of brain area and cognitive function of college students with significant stress symptoms were more obvious.

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