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Abstract #1681

Correlations between microstructural changes of anterior cingulum cortex and cerebral small vascular disease induced depression : A DKI Study

Zhenyu Pan1, Kun li1, Dongtao Liu2, Xiuqin Jia1, Qiao Bu1, Rui Jia1, Tao Jiang1, Yueluan Jiang3, Qinglei Shi3, and Lichun Zhou2
1Department of Radiology, Beijing Chao-Yang Hospital, Beijing, China, 2Department of Neurology, Beijing Chao-Yang Hospital, Beijing, China, 3MR Scientific Marketing, Diagnosis Imaging, Siemens Healthineers China, Beijing, China

Diffusion kurtosis imaging (DKI) is an advanced diffusion model based on an extender b value which characterizes water diffusion process as non-gaussian distribution, accordingly parameters derived from DKI are highly sensitive to changes in the microstructural tissue organization and the complexity of anisotropic environments. This study aimed to investigate the correlation between the microstructural changes of anterior cingulum cortex (ACC) and depression in patients with cerebral small vascular disease (CSVD) by applying diffusion Kurtosis imaging.

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