This study evaluates a feasibility of diffusion MRI based connectometry in capturing sports-related concussion (SRC) induced effects in adolescents using high school football players with and without concussion history as cohorts. The results revealed that although there were some common tract bundles whose segments showed significant correlation with concussion history independent of the diffusion metrics used (QA, MD, or FA), there were also different tract bundles that showed either positive or negative correlation with concussion depending on the diffusion metric used. A further study would be necessary to fully examine clinical relevance of this study’s findings in adolescents with SRC.
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