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Abstract #1702

Longitudinal Apparent Diffusion Coefficient Trajectory in Different Severity Outcome Following Experimental Neonatal Hypoxic Ischemia

Yu-Chieh Jill Kao1, Chia-Feng Lu1, Bao-Yu Hsieh2, Cheng-Yu Chen3, and Chao-Ching Huang4
1National Yang Ming University, Taipei, Taiwan, 2Chang-Gung University, Taoyuan, Taiwan, 3Taipei Medical University, Taipei, Taiwan, 4National Cheng Kung University, Tainan, Taiwan

Temporal and regional profile of ADC-related MR characteristics after neonatal hypoxic ischemia between mild and severe outcome was delineated at 6 h, 24 h and 7 days after injury. Significant difference in ADC trajectories obtained early after HI are observed between outcome groups, suggesting that distinct ADC changes may be associated to tissue damage severity along the progress of HI.

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