Abstract #1702

Longitudinal Apparent Diffusion Coefficient Trajectory in Different Severity Outcome Following Experimental Neonatal Hypoxic Ischemia

Yu-Chieh Jill Kao¹, Chia-Feng Lu¹, Bao-Yu Hsieh², Cheng-Yu Chen³, and Chao-Ching Huang⁴

¹National Yang Ming University, Taipei, Taiwan, ²Chang-Gung University, Taoyuan, Taiwan, ³Taipei Medical University, Taipei, Taiwan, ⁴National Cheng Kung University, Tainan, Taiwan

Temporal and regional profile of ADC-related MR characteristics after neonatal hypoxic ischemia between mild and severe outcome was delineated at 6 h, 24 h and 7 days after injury. Significant difference in ADC trajectories obtained early after HI are observed between outcome groups, suggesting that distinct ADC changes may be associated to tissue damage severity along the progress of HI.

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