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Abstract #1703

MIITRA atlas: Construction of high resolution T1w and DTI brain templates in a common space, based on 400 older adults

Yingjuan Wu1, Mohammad Rakeen Niaz1, Abdur Raquib Ridwan1, Xiaoxiao Qi1, David A. Bennett2, and Konstantinos Arfanakis1,2
1Illinois Institute of Technology, Chicago, IL, United States, 2Rush Alzheimer's Disease Center, Rush University, Chicago, IL, United States

As a critical step to establish the Multichannel Illinois Institute of Technology & Rush university Aging (MIITRA) atlas, the present work aimed to: a) develop high quality 0.5mm resolution T1-weighted (T1w) and diffusion tensor imaging (DTI) templates in a common space using data from a large, diverse, community cohort of non-demented older adults, and b) quantitatively compare the new templates to existing templates in terms of spatial normalization accuracy of external data. The new T1w and DTI templates allowed higher inter-subject and inter-modality spatial normalization of older adult data compared to other templates.

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