Hyperpolarized 129Xe gas lung MRI is an efficient technique used to investigate and assess pulmonary diseases. To improve the performance of 129Xe MRI in lung imaging a method for high-resolution 3D static ventilation images using FGRE combined with the key-hole method in a single breath-hold, was proposed. This technique acquires high-resolution 129Xe 3D static ventilation isotropic-voxel images from the COVID-19 survivors in a single breath-hold. The SNR of the images allowed for the analysis of VDP. This study confirms the feasibility of using isotropic-voxel acquisition sequence in a single breath-hold MRI to study the effects of COVID-19 on the lungs.