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Abstract #1743

Magnetic resonance fingerprinting in two-month-recovered COVID-19 patients

Yaping Wu1, Xianchang Zhang2, Yu Shen1, Yan Bai1, Wei Wei1, Congyu Liao3, and Meiyun Wang1
1Department of Medical Imaging, Henan Provincial People’s Hospital & the People’s Hospital of Zhengzhou University, Zhengzhou, China, 2MR Collaboration, Siemens Healthcare Ltd., Beijing, China, 3Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States

This study investigated the utility of magnetic resonance fingerprinting (MRF) to detect potential brain changes in recovered COVID-19 patients. MRF T1 and T2 maps of the brains of 8 recovered COVID-19 patients and 8 volunteers were non-linearly normalized into the MNI space to explore the differences between the groups using whole-brain analysis. COVID-19 patients had significantly lower T1 and T2 values in the left superior temporal gyrus, near the hub for the olfaction and gustation systems, and other brain areas. Our findings suggest that SARS-CoV-2 may widely affect the neurological system, and the effect persisted after more than two months.

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