Availability of clinical fMRI would be much improved via reduction of clinical exam times. A major factor in length of exam times is that typical MRI pulse sequences are optimized for a single image contrast (T1, T2, FLAIR, etc.) necessitating multiple pulse sequences each with significant “dead time” to acquire all desired contrasts for a given protocol. We here propose instead the time-efficient “prequence” (protocol sequence) concept which aims at acquisition of all desired contrasts in one or only a few sequences with minimal dead time. Preliminary proof-of-concept is demonstrated via a simultaneous T1/T2 contrast whole-brain neuro acquisition.
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