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Abstract #1834

Development of a simulation method to evaluate T2* shortening due to susceptibility of fat in the liver using the finite element method

Daiki Tamada1, Noriaki Nagata1, Ryoichi Kose2, Katsumi Kose2, Utaroh Motosugi3, and Hiroshi Onishi1
1Department of Radiology, University of Yamanashi, Chuo, Japan, 2MRIsimulations Inc., Tokyo, Japan, 3Department of Radiology, Kofu-Kyoritsu Hospital, Kofu, Japan

A method to simulate T2* shortening by the susceptibility of fat in the liver using FEM and simple modeling was developed. The model consisting of water and lipid droplets (LD) placed randomly. Simulation and in vivo studies indicated the feasibility of our method. The results suggested the microscopic field inhomogeneity by LDs leads to non-neglectable T2* decay. Besides, the result of in vivo study was fairly agreed with the simulation.

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