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Abstract #1836

Early results from a patient study aimed at testing a quantitative and synthetic brain MRI method, for abbreviated neuro protocols

Cheng-Chieh Cheng1, Jeffrey P. Guenette2, and Bruno Madore2
1Computer Science and Engineering, National Sun Yat-sen University, Kaohsiung, Taiwan, 2Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States

We developed a quantitative and synthetic MRI method capable of generating the most-commonly encountered contrasts in neuro protocols, along with quantitative parameter maps, with full brain coverage and 1-mm isotropic resolution, from only about 5 min of scanning. The eventual goal is for this sequence and associated processing to play a role in abbreviated neuro protocols. Promising results were obtained in healthy volunteers and we recently embarked on a larger patient study. After a few months of delay, largely associated with the pandemic, patient recruitment has started, and preliminary results are shown here.

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