Abstract #1851

High Temporal Resolution Wideband Dynamic Contrast-Enhanced Magnetic resonance imaging : The Mice Renal Function Study

Wei-Hao Huang¹, Chia-Ming Shih¹, Po-Wei Cheng¹, and Jyh-Horng Chen^1,2

¹Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan, Taipei, Taiwan, ²Interdisciplinary MRI/MRS Lab, Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan, Taipei, Taiwan

In this study, we aim to combine dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) and Wideband technique and use this accelerated sequence to assess the renal function of mice. With temporal resolution improvement, we can get more information in the same scan time, helping to perform a more accurate analysis. The quantitative analysis based on the Tofts model was performed and compare the result to the conventional DCE. All in all, we validate the feasibility of high temporal resolution Wideband DCE.

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