Abstract #1861

Perfusion mapping with sinusoidal CO2 respiratory challenge

Chau Vu¹, Jian Shen¹, Matthew Borzage², Soyoung Choi³, and John Wood⁴

¹Biomedical Engineering, University of Southern California, Los Angeles, CA, United States, ²Fetal and Neonatal Institute, Children's Hospital Los Angeles, Los Angeles, CA, United States, ³Neuroscience Graduate Program, University of Southern California, Los Angeles, CA, United States, ⁴Pediatrics and Radiology, Children's Hospital Los Angeles, Los Angeles, CA, United States

Dynamic susceptibility contrast MRI is a popular perfusion technique that requires the use of intravenous exogenous contrast. To avoid gadolinium injection, this study proposed a perfusion MRI method based on a CO₂ respiratory challenge, which delivers a sinusoidally-modulated CO₂ stimulus. We evaluated this technique at two different stimulus amplitudes and reported cerebral blood flow (CBF), cerebral blood volume (CBV) and transit time (TT) within the acceptable range of the previous literature.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.