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Abstract #1867

Automated pancreas sub-segmentation by groupwise registration and minimal annotation enables regional assessment of disease

Alexandre Triay Bagur1,2, Ged Ridgway2, Sir Michael Brady2,3, and Daniel Bulte1
1Department of Engineering Science, The University of Oxford, Oxford, United Kingdom, 2Perspectum Ltd, Oxford, United Kingdom, 3Department of Oncology, The University of Oxford, Oxford, United Kingdom

A method to automatically segment the pancreas into its main subcomponents head, body and tail is presented. The method uses groupwise registration to a reference template image that is subsequently annotated by parts. A new subject is registered to the template image, where part labels are propagated, and then transformed back to subject space. We test the method on the UK Biobank imaging sub-study, using a nominally healthy all-male cohort of 50 subjects for template creation and 20 other subjects for validation. We show pancreas T1 quantification by segment when reslicing the segmentation on a separate T1 slice.

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