Abstract #1870

Optimization of Flip Angle Modulated Motion Robust 2D Chemical Shift Encoded MRI of the Liver

Ruiyang Zhao^1,2, Jitka Starekova¹, Scott B Reeder^1,2,3,4,5, and Diego Hernando^1,2

¹Radiology, University of Wisconsin-Madison, Madison, WI, United States, ²Medical Physics, University of Wisconsin-Madison, Madison, WI, United States, ³Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States, ⁴Medicine, University of Wisconsin-Madison, Madison, WI, United States, ⁵Emergency Medicine, University of Wisconsin-Madison, Madison, WI, United States

Free breathing 2D flip angle modulated (FAM) CSE techniques along three separate orientations (axial/coronal/sagittal) were developed and validated for motion-robust free-breathing liver PDFF and R2* quantification. Six healthy volunteers were recruited and scanned at 3T. Promising results suggest that the proposed optimized 2D FAM CSE techniques along coronal and sagittal directions were able to avoid tissue slice gaps in the liver during free breathing acquisitions. Accurate quantification of PDFF and R2* were also observed with the proposed optimized techniques, as well as improved SNR performance compared to previously proposed low-flip angle 2D CSE.

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