Abstract #1891

Study on cerebral perfusion characteristic network of type 2 diabetes mellitus using 3D arterial spin labeling imaging

hang qu¹, wenjuan ba¹, weiqiang Dou², and wei wang¹

¹The Affiliated Hospital of Yangzhou University, yangzhou, China, ²GE Healthcare, MR Research China, Beijing, Beijing, China

This study aimed to investigate the cerebral microcirculatory blood flow perfusion and perfusion patterns in patients with type 2 diabetes by using 3D arterial spin labeling (ASL) imaging, and to analyze the correlation between perfusion changes and biochemical indexes. We obtained 3D-ASL derived cerebral blood flow (CBF) and perfusion feature network using principal component analysis (PCA) on each subject accordingly. These diabetic patients showed low regional CBF, and PCA-based perfusion characteristics could identify patients with diabetes. Changed perfusion patterns reflected the remodeling of cerebral blood flow perfusion, revealing clinical value and significance for early diagnosis and intervention of diabetic microangiopathy.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.