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Abstract #1892

Early Detection of Type 2 Diabetes Mellitus with Mild Cognitive Impairment based on Multiple Advanced Diffusion Models: DKI, MAP-MRI and NODDI

Wen-jiao Lyu1, Yunzhu Wu2, Xiao-meng Ma1, Yue Feng1, Yu-na Chen1, Shi-jun Qiu1, Xu Yan2, Min-xiong Zhou3, and Guang Yang4
1Department of Radiology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China, 2MR Scientific Marketing, SIEMENS Healthcare, Shanghai, China, 3Shanghai University of Medicine & Health Sciences, Shanghai, China, 4Shanghai Key Laboratory of Magnetic Resonance, East China Normal University, Shanghai, China

Compare to pathological examination and cognitive assessment scale, diffusion imaging can detect microscopic diffusion properties of biological tissues noninvasively and repeatably. This study aimed to evaluate the ability of multiple advanced diffusion models reconstructed by diffusion sequence: MAP-MRI, NODDI, and DKI in the early detection of Type 2 diabetes mellitus (T2DM) patients with mild cognitive impairment (MCI).

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