Abstract #1892

Early Detection of Type 2 Diabetes Mellitus with Mild Cognitive Impairment based on Multiple Advanced Diffusion Models: DKI, MAP-MRI and NODDI

Wen-jiao Lyu¹, Yunzhu Wu², Xiao-meng Ma¹, Yue Feng¹, Yu-na Chen¹, Shi-jun Qiu¹, Xu Yan², Min-xiong Zhou³, and Guang Yang⁴

¹Department of Radiology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China, ²MR Scientific Marketing, SIEMENS Healthcare, Shanghai, China, ³Shanghai University of Medicine & Health Sciences, Shanghai, China, ⁴Shanghai Key Laboratory of Magnetic Resonance, East China Normal University, Shanghai, China

Compare to pathological examination and cognitive assessment scale, diffusion imaging can detect microscopic diffusion properties of biological tissues noninvasively and repeatably. This study aimed to evaluate the ability of multiple advanced diffusion models reconstructed by diffusion sequence: MAP-MRI, NODDI, and DKI in the early detection of Type 2 diabetes mellitus (T2DM) patients with mild cognitive impairment (MCI).

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