Abstract #1896

Diffusion tensor imaging in the tibial nerve in patients with diabetic peripheral neuropathy

Nathan Davis¹, Steven Baete^2,3, Smita Rao⁴, Jill Slade⁵, Prodromos Parasoglou^2,3, and Ryan Brown^2,3

¹New York Institute of Technology, Old Westbury, NY, United States, ²Department of Radiology, Bernard and Irene Schwartz Center for Biomedical Imaging, New York University Grossman School of Medicine, New York, NY, United States, ³Department of Radiology, Center for Advanced Imaging Innovation and Research, New York University Grossman School of Medicine, New York, NY, United States, ⁴Department of Physical Therapy, New York University, New York, NY, United States, ⁵Department of Radiology, Michigan State University, East Langsing, MI, United States

Prolonged type 2 diabetes mellitus (T2DM) can result in diabetic peripheral neuropathy (DPN), a disease in which ischemic conditions degrade peripheral nerves. Diffusion tensor imaging (DTI) studies have demonstrated significant microstructural changes in upper extremity pathology, yet limited research has focused on the tibial nerve. We found cross-sectional differences in apparent diffusion coefficient between controls and T2DM and DPN. In a separate longitudinal study, insignificant DTI changes were found in DPN patients that were scanned before and after a 10-week exercise intervention.

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