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Abstract #2033

Analysis of high-resolution 3T diffusion MRI data obtained with minimal CUSP acquisition scheme from a Non-Human Primate

Alex Colin Valcourt Caron1, Amir Shmuel2, Ilana R. Leppert2, and Maxime Descoteaux1
1Université de Sherbrooke, Sherbrooke, QC, Canada, 2Montreal Neurological Institute, McGill University, Montreal, QC, Canada

The validation of advanced diffusion MRI methods requires acquisition at high-resolution and high SNR, which is difficult to obtain in humans. The use of anesthetized Non-Human Primates (NHPs) is key to unlocking valid microstructural maps. However, data acquisition and analysis tools must be adapted and configured for successful application to NHPs imaging. Here we propose a processing pipeline allowing for the analysis of diffusion data using DTI, CSD, and DIAMOND reconstruction, tailored for the analysis of data from the macaque brain. We present results obtained by applying the pipeline to a dataset acquired with a minimal CUSP 90 directions scheme.

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