Abstract #2065

Assessment of sex differences in ventricular-vascular coupling of left ventricular and aortic flow derived from 4D Flow MRI in healthy adults

Cody Johnson¹, Ryan Pewowaruk², David Rutkowski¹, Amanda Wolfinger¹, and Alejandro Roldán-Alzate^1,2,3

¹Radiology, University of Wisconsin-Madison, MADISON, WI, United States, ²Biomedical Engineering, University of Wisconsin-Madison, MADISON, WI, United States, ³Mechanical Engineering, University of Wisconsin-Madison, Madison, WI, United States

To gain insight into male-female differences in cardiovascular conditions, understanding healthy, sex differences is critical. We analyzed 20 healthy subjects with cardiac 4D flow MRI data (10 male and 10 female) to quantify LV and aortic flow, and ventricular vascular coupling (VVC) of KE and vorticity. The sex difference found in LV flow were not found in aortic flow. The VVC of LV-to-aortic flow was similar for men and women. The analysis methods and results of this study may be of further use in understanding ventricular vascular coupling of flow variables in various cardiovascular conditions.

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