Abstract #2066

Associations of Cardiac Rhythm with left atrial and left atrial appendage hemodynamics measured with 4D flow in Atrial Fibrillation

Amanda L DiCarlo¹, Justin Baraboo^1,2, Patrick McCarthy³, Rishi Arora⁴, Rod Passman⁴, Philip Greenland⁴, Daniel C Lee^1,4, Daniel Kim^1,2, and Michael Markl^1,2

¹Radiology, Northwestern University, Chicago, IL, United States, ²Biomedical Engineering, Northwestern University, Chicago, IL, United States, ³Cardiac Surgery, Northwestern University, Chicago, IL, United States, ⁴Cardiology, Northwestern University, Chicago, IL, United States

Atrial fibrillation (AF) is the most common cardiac arrhythmia, characterized by irregular heart rhythm which can lead to stroke due to thrombus formation in the left atrium (LA) or left atrial appendage (LAA). Reduced velocities and increased stasis measured with 4D flow MRI are risk metrics correlated with LA thrombus formation and potential predictors of stroke. This study analyzed the relationship between heart rate variability derived from a real time MRI acquisition and 4D flow hemodynamic risk metrics. LA peak velocity and stasis were significantly correlated with heart rate variability, suggesting a link between rhythm status and thrombus risk.

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