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Abstract #2066

Associations of Cardiac Rhythm with left atrial and left atrial appendage hemodynamics measured with 4D flow in Atrial Fibrillation

Amanda L DiCarlo1, Justin Baraboo1,2, Patrick McCarthy3, Rishi Arora4, Rod Passman4, Philip Greenland4, Daniel C Lee1,4, Daniel Kim1,2, and Michael Markl1,2
1Radiology, Northwestern University, Chicago, IL, United States, 2Biomedical Engineering, Northwestern University, Chicago, IL, United States, 3Cardiac Surgery, Northwestern University, Chicago, IL, United States, 4Cardiology, Northwestern University, Chicago, IL, United States

Atrial fibrillation (AF) is the most common cardiac arrhythmia, characterized by irregular heart rhythm which can lead to stroke due to thrombus formation in the left atrium (LA) or left atrial appendage (LAA). Reduced velocities and increased stasis measured with 4D flow MRI are risk metrics correlated with LA thrombus formation and potential predictors of stroke. This study analyzed the relationship between heart rate variability derived from a real time MRI acquisition and 4D flow hemodynamic risk metrics. LA peak velocity and stasis were significantly correlated with heart rate variability, suggesting a link between rhythm status and thrombus risk.

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