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Abstract #2078

Computationally Enhanced 4D Flow MRI for the Assessment of Pre- and Post-Coarctation Repair Aorta Flow Dynamics

Labib Shahid1, James Rice1, Haben Berhane2, Cynthia Rigsby3, Joshua Robinson3, Lindsay Griffin3, Michael Markl2, and Alejandro Roldán-Alzate1
1University of Wisconsin-Madison, Madison, WI, United States, 2Northwestern University, Chicago, IL, United States, 3Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, United States

CMR is used for diagnosis of COA and post-intervention assessment. Current limitations of 4D flow MRI include insufficient spatio-temporal resolution, inability to image low velocity regions, and distortion of image due to stent. The presented MRI-based computational enhancement method addresses stated limitations. Patient specific flow velocities defined the boundary conditions for numerical simulations. CFD simulations with AMR were run on segmented aorta geometries. Comparison between in-vivo and CFD results show good agreement, and residual complex flows post-repair compared to healthy control. Computational enhancement of 4D flow MRI can be used as a predictive tool in future clinical settings.

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