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Abstract #2087

Whole-heart 4D flow MRI: comparison between pseudo-spiral undersampling with compressed sensing reconstruction and EPI readout

Carmen P S Blanken1, Lukas M Gottwald2, Jos J M Westenberg3, Eva S Peper2, Bram F Coolen4, Gustav J Strijkers4, Aart J Nederveen2, R Nils Planken2, and Pim van Ooij2
1Radiology and Nuclear Medicine, Amsterdam UMC, Amsterdam, Netherlands, 2Radiology and Nuclear Medicine, Amsterdam UMC, location AMC, Amsterdam, Netherlands, 3Radiology, Leiden UMC, Leiden, Netherlands, 4Biomedical Engineering and Physics, Amsterdam UMC, location AMC, Amsterdam, Netherlands

We compare pseudo-spiral undersampled whole-heart 4D flow MRI with CS reconstruction with a clinically used EPI readout in a cohort of healthy subjects and patients with valve regurgitation. Our results indicate that pseudo-spiral CS 4D flow MRI is at least as reliable as EPI-based 4D flow MRI in terms of inter-valve consistency of blood flow measurements and agreement with 2D MRI-based regurgitant volume measurement. Doubling the undersampling factor of the CS acquisition results in <10% deviation of the measurements compared to the original acquisition, suggesting that CS scan times may be shortened to expedite clinical implementation.

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