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Abstract #2088

Echo Planar Imaging induced errors in intracardiac 4D MRI flow quantification

Jos J.M. Westenberg1, Hans C van Assen1, Pieter J van den Boogaard1, Jelle J Goeman1, Hicham Saaid2, Jason Voorneveld3, Johan Bosch3, Sasa Kenjeres4, Tom Claessens2, Pankaj Garg5, Marc Kouwenhoven6, and Hildo J Lamb1
1Leiden University Medical Center, Leiden, Netherlands, 2Ghent University, Ghent, Belgium, 3Erasmus Medical Center, Rotterdam, Netherlands, 4University of Technology Delft, Delft, Netherlands, 5Norwich University Hospital, Norwich, United Kingdom, 6Philips Healthcare, Best, Netherlands

Echo Planar Imaging (EPI) is associated with inaccurate velocity quantitation in 4D flow MRI. The systematic errors depend on the orientation of readout and blip phase encoding gradient with respect to the flow direction. This study evaluates EPI-related errors in flow rate and velocity quantitation for in vivo intracardiac 4D flow MRI in a phantom and in ten healthy volunteers. Errors in median flow rate and velocity remain below 10% for normal in vivo intracardiac flow with EPI factor 5. The error is smallest when readout and blip phase encoding gradients are both perpendicular to the main flow.

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