Abstract #2093

Evaluating ICOSA6 4D-Flow in a Compliant Aortic Dissection Model with Large Velocity Range and Complex Flow Patterns.

Judith Zimmermann^1,2, Michael Loecher^1,3, Tyler Cork^1,4, Kathrin Bäumler¹, Alison Marsden^5,6,7, Dominik Fleischmann^1,7, and Daniel Ennis^1,3,7

¹Radiology, Stanford University, Stanford, CA, United States, ²Computer Science, Technical University of Munich, Munich, Germany, ³Radiology, Veterans Affairs Health Care System, Palo Alto, CA, United States, ⁴Bioengineering, Stanford University, Palo Alto, CA, United States, ⁵Pediatrics, Stanford University, Stanford, CA, United States, ⁶Bioengineering, Stanford University, Stanford, CA, United States, ⁷Cardiovascular Institute, Stanford University, Stanford, CA, United States

Goal: To assess flow quantitation with multi-directional (ICOSA6) high-moment 4D-flow in a compliant type-B aortic dissection model that provides complex flow and a large velocity range. An in vitro flow setup was designed to acquire prolonged 4D-flow imaging in a flow- and pressure-controlled environment. ICOSA6 4D-flow data was acquired with a highly-sampled stack-of-stars scheme, reconstructed with varying under-sampling factors (R=5-65), and compared to a four-point Cartesian-sampled 4D-flow sequence. Results showed average net flow difference within the ±5% margin for ICOSA6 data under-sampled with up to R=40. Peak velocity, however, differed greatly for all ICOSA6 data when compared to four-point Cartesian.

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