Abstract #2092

Impact of gadolinium contrast on image quality and quantitative flow assessment using conventional and compressed sensing 4D flow prototypes

Tilman Stephan Emrich^1,2,3, Natalie Ring², U. Joseph Schoepf¹, Ning Jin⁴, Daniel Sebastian Dohle⁵, Fei Xiong⁴, Anna Lena Emrich^5,6, Karl-Friedrich Kreitner², and Akos Varga-Szemes¹

¹Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC, United States, ²Radiology, University Medical Center Mainz, Mainz, Germany, ³DZHK, Partner-Site Rhine-Main, Mainz, Germany, ⁴Siemens Medical Solutions USA, Inc., Chicago, IL, United States, ⁵Department of Cardiothoracic Surgery, University Medical Center Mainz, Mainz, Germany, ⁶Department of Cardiothoracic Surgery, Medical University of South Carolina, Charleston, SC, United States

This study investigates the effect of the presence of gadolinium contrast on image quality and quantitative flow assessment using conventional and highly accelerated compressed sensing (CS) 4D flow prototypes. In our cohort of 18 healthy volunteers who underwent pre- and post-contrast 4D flow measurements using both techniques, strong to very strong agreement in quantitative flow measurements were found between pre- and post-contrast studies and between conventional and CS 4D flow measurements. SNR was significantly increased after contrast injection in both prototype measurements. Our results suggest that 4D flow acquisition provides accurate flow assessment regardless of the presence of contrast agent.

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