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Abstract #2091

A Pulse Wave Velocity Calculation Tool for 4D flow MRI – Data Requirements and Application in Marfan Patients

Eric Schrauben1, Mitzi van Andel2, Lukas Gottwald1, Aart Nederveen1, Maarten Groenink1,2, and Pim van Ooij1
1Department of Radiology & Nuclear Medicine, Amsterdam University Medical Centers, location AMC, Amsterdam, Netherlands, 2Department of Cardiology, Amsterdam University Medical Centers, location AMC, Amsterdam, Netherlands

Aortic pulse wave velocity (PWV), which can be an indicator of certain cardiovascular disease via aortic stiffness estimation, requires high temporal resolution for accurate measurements. Using compressed sensing based 4D flow MRI of the aorta, we propose a tool for assessment of PWV. The impact of data requirements (and thereby scan time) were investigated via retrospective undersampling in a cohort of healthy volunteers. The findings were then applied to Marfan subjects to determine if the minimal data requirements effectively detect differences between patients and healthy controls.

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