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Abstract #2097

Patient-Specific, In-Vitro Modeling of Aortic Coarctation Using 4D Flow MRI and Particle Image Velocimetry 

James Rice1, Labib Shahid1, Haben Berhane2, Joshua Robinson3, Lindsay Griffin3, Cynthia Rigsby3, Michael Markl2, and Alejandro Roldan-Alzate1
1University of Wisconsin-Madison, Madison, WI, United States, 2Northwestern University, Evanston, IL, United States, 3Lurie Children's Hospital, Chicago, IL, United States

4D flow MRI can be used to assess COA repair hemodynamics in-vivo, albeit, after surgery is performed. This study develops a modeling and validation framework for in-vitro COA hemodynamic assessment. Patient-specific in-vitro models were created representing pre- and post- repair COA aortic geometries. 4D flow was employed to assess model hemodynamics. A PIV protocol was developed to assess the validity of the 4D flow MRI results. PIV velocities qualitatively agreed with 4D flow MRI. In-vitro 4D flow MRI can be used as a predictive tool for COA that can be enhanced with PIV validation.

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