Aortic valve (AV) conditions cause extra burden to the heart and frequently lead to clinicalintervention. In the present study we set a 4D-flow-MRI framework to evaluate in-vitro personalizedcompliant 3D-printed AV. We evaluated a healthy and three diseased AV under rest to stresspulsatile flow conditions. The results obtained provide further evidence that trans-valvular non-invasive pressure drop is estimated more accurately accounting for full velocity profile, via thesimplified advective work-energy relative pressure (SAW), than accounting solely for the maximalvelocity as it is clinically stablished. Both the methodology and the findings can potentially improveclinical decision-making.
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