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Abstract #2115

Application of APT and DKI in predicting the postoperative liver decompensation and recurrence of early HCC after TACE treatment

Cai ming xi1, Han dong ming1, and Wang kai yu2
1The First Affiliated Hospital of Xinxiang Medical University, Xinxiang, China, 2GE Healthcare, MR Research China, Beijing, China

In this study we assessed the feasibility of quantitative parameters derived from amide proton transfer (APT) and diffusion kurtosis imaging (DKI) in predicting the response to transcatheter arterial chemoembolization (TACE) treatment for hypervascular hepatocellular carcinoma (HCC). The combination model of quantitative parameters of APT and DKI showed good diagnostic performance in predicting the recurrence and postoperative liver decompensation. Therefore, APT and DKI can be used as potential imaging biomarkers to predict the effect of early-stage HCC after TACE treatment.

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