Abstract #2119

Noninvasive Diagnosis of Portal Hypertension and Screening Varices with 4D Flow MRI: A Pilot Study

Jiachen Ji¹, Changchun Liu², Yunduo Li¹, Mingzhu Fu¹, Jinghui Dong², Jianming Cai², Chunsheng Chi³, Bo Jin³, Wen Shen⁴, Xiaolong Qi⁵, and Rui Li¹

¹Center for Biomedical Imaging Research, Department of Biomedical Engineering, Tsinghua University, Beijing, China, ²Department of Radiology, The Fifth Medical Centre of Chinese PLA General Hospital, Beijing, China, Beijing, China, ³First Liver Cirrhosis Diagnosis and Treatment Center, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, China, Beijing, China, ⁴Department of Radiology, First Center Hospital of Tianjin, Tianjin, China, Tianjin, China, ⁵CHESS Center, Institute of Portal Hypertension, The First Hospital of Lanzhou University, Lanzhou, China, Lanzhou, China

Portal hypertension (PH) is a severe liver disease which could lead to gastroesophageal varices. Noninvasive methods to diagnose PH and to evaluate the risk of variceal bleeding are needed. 4D Flow MRI is an advanced technique which could provide visualization and quantification of blood flow. In the study, we identified the reproducibility of the processing and quantifying procedure of 4D Flow data and discovered the significant hemodynamic differences in portal vein between PH patients and controls using 4D Flow MRI. Additionally, we tested the performance of 4D Flow MRI in diagnosing PH and stratifying the risk of variceal bleeding.

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