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Abstract #2119

Noninvasive Diagnosis of Portal Hypertension and Screening Varices with 4D Flow MRI: A Pilot Study

Jiachen Ji1, Changchun Liu2, Yunduo Li1, Mingzhu Fu1, Jinghui Dong2, Jianming Cai2, Chunsheng Chi3, Bo Jin3, Wen Shen4, Xiaolong Qi5, and Rui Li1
1Center for Biomedical Imaging Research, Department of Biomedical Engineering, Tsinghua University, Beijing, China, 2Department of Radiology, The Fifth Medical Centre of Chinese PLA General Hospital, Beijing, China, Beijing, China, 3First Liver Cirrhosis Diagnosis and Treatment Center, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, China, Beijing, China, 4Department of Radiology, First Center Hospital of Tianjin, Tianjin, China, Tianjin, China, 5CHESS Center, Institute of Portal Hypertension, The First Hospital of Lanzhou University, Lanzhou, China, Lanzhou, China

Portal hypertension (PH) is a severe liver disease which could lead to gastroesophageal varices. Noninvasive methods to diagnose PH and to evaluate the risk of variceal bleeding are needed. 4D Flow MRI is an advanced technique which could provide visualization and quantification of blood flow. In the study, we identified the reproducibility of the processing and quantifying procedure of 4D Flow data and discovered the significant hemodynamic differences in portal vein between PH patients and controls using 4D Flow MRI. Additionally, we tested the performance of 4D Flow MRI in diagnosing PH and stratifying the risk of variceal bleeding.

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