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Abstract #2122

Echo time dependence of the biexponential and triexponential IVIM parameters in the liver

Tobit Führes1, Andreas Julian Riexinger1, Jan Martin2, Martin Gerhard Loh1, Bernhard Hensel3, Michael Uder1, and Frederik Bernd Laun1
1University Hospital Erlangen, Erlangen, Germany, 2Lund University, Lund, Sweden, 3Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany

In this study, we acquired diffusion-weighted image data of 15 healthy volunteers at four different TE. A ROI-based IVIM analysis showed that the pseudodiffusion coefficients did not change with TE, whereas the perfusion fractions rose significantly for bi- and triexponential IVIM curves at longer TE. A quantitative analysis indicates that the triexponential perfusion fractions are unlikely attributable to venous and arterial blood compartments. Our results indicate moreover that the pseudodiffusion coefficients can be compared without TE-correction among studies performed with different TE.

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