Abstract #2121

Microvascular Invasion has no Independent Effect on Recurrence in Small Hepatocellular Carcinoma: A Propensity Score Matching Analysis

Huan-Huan Chong^1,2, Pei-Yun Zhou^3,4, Chun Yang², and Meng-Su Zeng^1,2,5

¹Shanghai Institute of Medical Imaging, Shanghai, China, ²Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai, China, ³Department of Liver Surgery, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China, ⁴Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Shanghai, China, ⁵Department of Medical Imaging, Shanghai Medical College, Fudan University, Shanghai, China

Whether microvascular invasion (MVI) is a prognosis factor for small hepatocellular carcinoma (sHCC) is controversial, a preoperatively predictive model based on gadoxetate disodium (Gd-EOB-DTPA) MRI is clinical needed for MVI in sHCC.We concluded that alpha-fetoprotein>20 ng/mL, non-smooth margin, incomplete or absent capsule, peritumoral enhancement and larger tumor size were independent risk factors for MVI in patients with sHCC ≤3 cm. Although MVI independently impaired RFS before propensity score matching (PSM), it was ultimately identified as a potential but not an independent risk factor for recurrence in sHCC patients after PSM balancing the confounder — tumor size.

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