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Abstract #2121

Microvascular Invasion has no Independent Effect on Recurrence in Small Hepatocellular Carcinoma: A Propensity Score Matching Analysis

Huan-Huan Chong1,2, Pei-Yun Zhou3,4, Chun Yang2, and Meng-Su Zeng1,2,5
1Shanghai Institute of Medical Imaging, Shanghai, China, 2Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai, China, 3Department of Liver Surgery, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China, 4Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Shanghai, China, 5Department of Medical Imaging, Shanghai Medical College, Fudan University, Shanghai, China

Whether microvascular invasion (MVI) is a prognosis factor for small hepatocellular carcinoma (sHCC) is controversial, a preoperatively predictive model based on gadoxetate disodium (Gd-EOB-DTPA) MRI is clinical needed for MVI in sHCC.We concluded that alpha-fetoprotein>20 ng/mL, non-smooth margin, incomplete or absent capsule, peritumoral enhancement and larger tumor size were independent risk factors for MVI in patients with sHCC ≤3 cm. Although MVI independently impaired RFS before propensity score matching (PSM), it was ultimately identified as a potential but not an independent risk factor for recurrence in sHCC patients after PSM balancing the confounder — tumor size.

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