Abstract #2139

Quantitative Assessment of Liver Function by using Hepatocyte Fraction based on Gd-EOB-DTPA-Enhanced MRI

Xueqin ZHANG¹, Jian LU¹, Jifeng JIANG¹, and Weibo CHEN²

¹the Third People’s Hospital of Nantong, Nantong, China, ²Philips Healthcare, Shanghai, China

The purpose of this study was to assess the ability of hepatocyte fraction on Gd-EOB-DTPA-enhanced MRI for the quantitative evaluation of liver function. We used Look-Locker sequences to acquire T1 mapping images pre and post-contrast at 20 minutes after Gd-EOB-DTPA administration. T1 relaxation times (T1pre and T1post) of the liver, reduction rates of T1 relaxation times (rrT1), hepatocyte fraction (HeF) and K_Hep were measured. Our study showed that T1post, rrT1, HeF and K_Hep vlaues based on Gd-EOB-DTPA-enhanced T1 mapping MRI are efficient diagnostic tools for the quantitative evaluation of liver function.

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