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Abstract #2139

Quantitative Assessment of Liver Function by using Hepatocyte Fraction based on Gd-EOB-DTPA-Enhanced MRI

Xueqin ZHANG1, Jian LU1, Jifeng JIANG1, and Weibo CHEN2
1the Third People’s Hospital of Nantong, Nantong, China, 2Philips Healthcare, Shanghai, China

The purpose of this study was to assess the ability of hepatocyte fraction on Gd-EOB-DTPA-enhanced MRI for the quantitative evaluation of liver function. We used Look-Locker sequences to acquire T1 mapping images pre and post-contrast at 20 minutes after Gd-EOB-DTPA administration. T1 relaxation times (T1pre and T1post) of the liver, reduction rates of T1 relaxation times (rrT1), hepatocyte fraction (HeF) and KHep were measured. Our study showed that T1post, rrT1, HeF and KHep vlaues based on Gd-EOB-DTPA-enhanced T1 mapping MRI are efficient diagnostic tools for the quantitative evaluation of liver function.

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