To explore parameters obtained by Gd-EOB-DTPA T1 mapping and extracellular volume fraction in evaluating hepatic fibrosis (HF) in a rabbit model. The HF model was established by carbon tetrachloride (CCl4).Rabbits underwent pathological examination to determine the HF stage using the metavir classification system. Parameters including T1native, T110 min, T120 min, ECV10 min and ECV20 min were measured and compared among the different HF stages using spearman correlation coefficients and receiver operating characteristic curve. The AUC of T120 min was higher than that of other quantitative parameters. T1 mapping parameters and ECV fraction are closely associated with HF progression.
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