A range of severe liver diseases are identified only in very late stages. At a late stage, the only remaining treatment may be resective liver surgery. The resection can lead to serious complications if the remnant tissue fails to match the requirement of liver function. Therefore, it is valuable to accurately measure both regional and global liver function to better predict the outcome of the surgery. Here we use DCE-MRI to show that there are differences in Gadoxetate uptake both between patients and regional difference between the adjacent segments before and after resective surgery.