Abstract #2141

Regional Liver Function Pre- and Post-Resective Liver Surgery in Patients

Christian Simonsson^1,2, Markus Karlsson¹, Nils Dahlström¹, Peter Lundberg^1,2, Wolf Claus Bartholomä^1,2, Gunnar Cedersund^2,3, Per Sandström⁴, and Anna Lindhoff Larsson3⁴

¹Department of Radiation Physics, Radiology, Linköping University, Linköping, Sweden, ²Center for Medical Image Science and Visualization (CMIV), Linköping University, Linköping, Sweden, ³Department of Medical Engineering, Linköping University, Linköping, Sweden, ⁴3Department of Surgery, Department of biomedical and clinical sciences, Linköping University, Linköping, Sweden

A range of severe liver diseases are identified only in very late stages. At a late stage, the only remaining treatment may be resective liver surgery. The resection can lead to serious complications if the remnant tissue fails to match the requirement of liver function. Therefore, it is valuable to accurately measure both regional and global liver function to better predict the outcome of the surgery. Here we use DCE-MRI to show that there are differences in Gadoxetate uptake both between patients and regional difference between the adjacent segments before and after resective surgery.

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