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Abstract #2152

Are rapid structural scans viable for automated lesion assessment in MS patients ?

Mathilde Carrière1, Bénédicte Maréchal2,3,4, Jérémy Deverdun1, Thomas Troalen5, Tobias Kober2,3,4, Ricardo Corredor-Jerez2,3,4, and Emmanuelle Le Bars1
1I2FH, Neuroradiology, CHU Montpellier, University of Montpellier, Montpellier, France, 2Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland, 3Department of Radiology, Lausanne University Hospital and University of Lausanne, Département de radiologie, Hôpital Universitaire de Lausanne et Université de Lausanne (UNIL), Lausanne, Switzerland, 4LTS 5, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, 5Siemens SAS Healthcare, Saint-Denis, France

Current MR protocol guidelines for multiple sclerosis (MS) diagnosis and follow-up recommend the acquisition of 3D sequences as high isotropic resolution improves lesion conspicuity; however, this prolongs clinical scan protocols. We present a qualitative and quantitative comparison of lesion assessment using a standard 3D FLAIR and an optimized CAIPIRINHA version in conjunction with compressed sensing MPRAGE in 44 MS patients. We compared the automated lesion segmentation results between protocols, with and without additional manual corrections of the lesion masks. Volumes using the optimized protocol highly correlated with the results from the conventional protocol, while reducing the acquisition time by 47%.

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