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Abstract #2183

Impact of motion on simultaneously acquired PET/MRI of myocardial infarcted heart.

Heeseung Lim1, Benjamin Wilk 1,2, Jane Sykes 1, John Butler 1, Gerald Moran3, Jonathan Thiessen1,2, Gerald Wisenberg1,4, and Frank S Prato1,2
1Lawson Health Research Institute, London, ON, Canada, 2Medical Biophysics, Western University, London, ON, Canada, 3Siemens Healthcare Limited, Oakville, ON, Canada, 4MyHealth Centre, Arva, ON, Canada

This study investigates the impact of motion in myocardial PET/MRI data by registering pre-mortem images to post-mortem images from a simultaneously acquired PET/MRI scan. After a registration in MRI, PET data is transformed and analyzed using the Patlak model. There are significant differences and correlation between pre- and post-mortem PET images. There are discrepancies in different segments of heart, but none were found to be significantly different. These results suggest that the level of inflammation in the heart might be misrepresented. Further comparison with motion corrected images will provide more concrete discrepancy due to motion for myocardial PET/MRI imaging.

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