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Abstract #2207

Echo-planar Spectroscopic Imaging with Readout-segmented COKE at 7T:  Artifact Analysis using a Purpose-Built Phantom and Simulation

Graeme A. Keith1, Amir Seginer2, David A. Porter1, and Rita Schmidt3
1Institute of Neuroscience and Psychology, University of Glasgow, Glasgow, Scotland, 2Siemens Healthcare Ltd, Rosh Ha’ayin, Israel, 3Neurobiology Department, Weizmann Institute of Science, Rehovot, Israel

Echo-planar spectroscopic imaging (EPSI) is a fast method of acquiring metabolic information in the human brain. When applied at high-fields, such as 7T however, it suffers from limited spectral-width, as well as the inconsistencies between readout lines, seen at all field strengths, which lead to ghosts in the spectra. In this work, we present the readout-segmented COKE method, which removes the spectral-width limitation at 7T and provides a coherent phase evolution that avoids Nyquist artefacts in the spectra. Simulations and phantom scans are also presented, which seek to increase understanding of residual lipid contamination due to the readout-segmented spatial-encoding scheme.

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