Abstract #2208

Whole Brain 3D-FIDESI-MRSI: Revisiting Free-Induction-Decay & Spin-Echo Readouts with Concentric Rings at 7 T

Lukas Hingerl¹, Wolfgang Bogner¹, Bernhard Strasser¹, Petr Bednarik¹, Stanislav Motyka¹, Eva Heckova¹, Ivica Just¹, Alexandra Lipka¹, Ovidiu Andronesi², Stephan Gruber¹, Siegfried Trattnig^1,3, and Gilbert Hangel^1,4

¹Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, High Field MR Centre, Vienna, Austria, ²Department of Radiology, Massachusetts General Hospital, Martinos Center for Biomedical Imaging, Boston, MA, United States, ³Christian Doppler Laboratory for Clinical Molecular MR Imaging, Vienna, Austria, ⁴Department of Neurosurgery, Medical University of Vienna, Vienna, Austria

3D-FIDESI-MRSI combines a free-induction-decay-readout with an echo-readout to permit the measurement of whole-brain lactate as an important tumor biomarker in approximately 40 min. This enables the acquisition of signals at short TE with reduced T2-weighting as well as spectra at long TE without lipid contamination. Sufficient SNR is ensured by a smaller and oversampled spherical k-space coverage for the echo-readout using fast concentric ring trajectories. A test in a healthy volunteer successfully demonstrates feasible mapping of the major metabolites.

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