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Abstract #2208

Whole Brain 3D-FIDESI-MRSI: Revisiting Free-Induction-Decay & Spin-Echo Readouts with Concentric Rings at 7 T

Lukas Hingerl1, Wolfgang Bogner1, Bernhard Strasser1, Petr Bednarik1, Stanislav Motyka1, Eva Heckova1, Ivica Just1, Alexandra Lipka1, Ovidiu Andronesi2, Stephan Gruber1, Siegfried Trattnig1,3, and Gilbert Hangel1,4
1Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, High Field MR Centre, Vienna, Austria, 2Department of Radiology, Massachusetts General Hospital, Martinos Center for Biomedical Imaging, Boston, MA, United States, 3Christian Doppler Laboratory for Clinical Molecular MR Imaging, Vienna, Austria, 4Department of Neurosurgery, Medical University of Vienna, Vienna, Austria

3D-FIDESI-MRSI combines a free-induction-decay-readout with an echo-readout to permit the measurement of whole-brain lactate as an important tumor biomarker in approximately 40 min. This enables the acquisition of signals at short TE with reduced T2-weighting as well as spectra at long TE without lipid contamination. Sufficient SNR is ensured by a smaller and oversampled spherical k-space coverage for the echo-readout using fast concentric ring trajectories. A test in a healthy volunteer successfully demonstrates feasible mapping of the major metabolites.

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