The goal of this abstract was to deepen the knowledge on the influence of LCModel fitting parameters and SNR on GABA quantification and on the sensitivity for detecting differences in GABA levels. To this aim, GABA concentrations were quantified using different LCModel approaches and different number of averages in synthetically altered spectra generated by adding synthetic GABA signal to in-vivo ultra-short TE, 7-T human spectra.
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