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Abstract #2219

Assessing the agreement between 3T and 7T MRS measures of in-vivo neurochemistry.

Dana Goerzen1,2, Tiffany Bell3,4,5, Jamie Near1,2, and Ashley D Harris3,4,5
1McGill University, Montreal, QC, Canada, 2Centre d'Imagerie Cérébrale, Douglas Mental Health University Institute, Montreal, QC, Canada, 3Radiology, University of Calgary, Calgary, AB, Canada, 4Hotchkiss Brain Institution, Calgary, AB, Canada, 5Alberta Children's Hospital Research Institute, Calgary, AB, Canada

A key challenge in magnetic resonance spectroscopy in the human brain is assessing the reliability of metabolite concentration estimates, since the ground truth is generally unknown. This project assesses the correlations between 3T MRS metabolite measures against two “gold standard” 7T sequences as a means to assess which 3T sequences are the most reliable at detecting common metabolites of interest. This work will help researchers to make informed choices about which sequences to use for optimal detection of their metabolites of interest.

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