Abstract #2219

Assessing the agreement between 3T and 7T MRS measures of in-vivo neurochemistry.

Dana Goerzen^1,2, Tiffany Bell^3,4,5, Jamie Near^1,2, and Ashley D Harris^3,4,5

¹McGill University, Montreal, QC, Canada, ²Centre d'Imagerie Cérébrale, Douglas Mental Health University Institute, Montreal, QC, Canada, ³Radiology, University of Calgary, Calgary, AB, Canada, ⁴Hotchkiss Brain Institution, Calgary, AB, Canada, ⁵Alberta Children's Hospital Research Institute, Calgary, AB, Canada

A key challenge in magnetic resonance spectroscopy in the human brain is assessing the reliability of metabolite concentration estimates, since the ground truth is generally unknown. This project assesses the correlations between 3T MRS metabolite measures against two “gold standard” 7T sequences as a means to assess which 3T sequences are the most reliable at detecting common metabolites of interest. This work will help researchers to make informed choices about which sequences to use for optimal detection of their metabolites of interest.

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