Abstract #2276

Quantitative bone marrow MRI in children with leukaemia

Nataliia Kriventsova¹, Petr Menshchikov², Dmitry Kupriyanov², Dmitry Litvinov¹, Galina Novichkova¹, and Galina Tereshchenko¹

¹Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russian Federation, ²Philips Healthcare, Moscow, Russian Federation

In our study, we quantified the bone marrow fat fraction (FF) using mDixon-Quant MRI and MR Spectroscopy. The FF values in the bone marrow in children with acute leukemia compared with children of the same age without hematological diseases were significantly different. The value of the fat fraction may become an MR-biomarker of bone marrow in children with acute leukemia.

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