Meeting Banner
Abstract #2342

Intravoxel incoherent motion diffusion-weighted MR imaging for preoperatively identifying CK19-positive hepatocellular carcinoma

Ying Zhao1, Ailian Liu1, Wenjing Qi2, Xue Ren1, Tao Lin1, and Qingwei Song1
1The First Affiliated Hospital of Dalian Medical University, Dalian, China, 2Department of Pathology, The First Affiliated Hospital, Dalian Medical University, Dalian, China

Cytokeratin 19 (CK19) is well acknowledged as a biliary/progenitor cell marker and a marker of tumor stem cell. CK19-positive HCCs demonstrate more aggressive behaviors and poorer outcomes. This worked aimed at exploring the value of intravoxel incoherent motion (IVIM) diffusion-weighted (DW) magnetic resonance (MR) imaging in the diagnosis of CK19-positive HCC. The results showed that Slow ADC Mono and Slow ADC Bi were significantly different between the CK19-positive and CK19-negative HCC groups. The area under the curves (AUCs) of Slow ADC Mono, Slow ADC Bi, and combine (Slow ADC Mono & Slow ADC Bi) were 0.817, 0.988, and 0.992, respectively.

This abstract and the presentation materials are available to members only; a login is required.

Join Here