The aim of this study was to explore the value of intratumoral susceptibility signal intensities (ITSS) in quantitatively and automatically differentiating intrahepatic cholangiocarcinoma (ICC) from hepatocellular carcinoma (HCC) using enhanced T2 star-weighted angiography (ESWAN). The results showed that quantitative ITSS could provide a promising differential performance (AUC = 0.927, sensitivity = 85%, specificity = 92.3%) in quantitatively differentiating ICC from HCC.
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